The title refers to two grandfathers both named Bill: The one on his mother's side was associated with gangsters and served prison time for armed robbery; he credits the one on his father's side with leading him on the path to Cambridge University.
Streeting got into politics at a young age, leading the Cambridge student union and becoming president of the National Union of Students. He later worked for Stonewall, an LGBTQ+ group, and has spoken of his struggle coming out as gay and reconciling his sexuality with his Anglican faith.
He served as a councilor in local government and later deputy leader of the council in the east London borough of Redbridge before being elected to Parliament in 2015.
He was a backbench lawmaker under Labour leader Jeremy Corbyn, a veteran socialist whose time in charge saw the party lose two elections and face allegations of antisemitism in its ranks. Streeting, long critical of Corbyn, was promoted after Starmer took over as leader in 2020.
Streeting's Cabinet position became a personal mission to fix an ailing National Health Service because of his own battle with kidney cancer.