"It's with mixed emotions that the upcoming India series will be my last for Australia," she said on Tuesday. "I'm still passionate about playing for Australia but I've somewhat lost that competitive edge that's kept me driven since the start, so the time feels right to call it a day.
"Knowing I won't be going to the T20 World Cup this year and the limited preparation time the team has, I won't be part of the T20s against India, but I'm excited to have the opportunity to finish my career and captain the ODI and test side at home against India - one of the biggest series on the calendar for us."
The series with India features three T20s from Feb. 15-21, followed by three one-day internationals from Feb. 24-March 1 and finishing with a test in Perth from March 6-9.
If she plays five of the matches she will reach 300 internationals.
Healy has also done television commentary for the past several years including during the recent Ashes series that she missed because of injury. She is married to Australia fast bowler Mitchell Starc and is the niece of former Australia wicketkeeper Ian Healy.